Protection and barrier effect

Evaluation of barrier effects on 3D reconstructed human epidermis

Regulatory reference: Proprietary method
Claim: Protects and repairs the cutaneous barrier
Application field: Topical products.
Description of the test: Evaluation on 3D in vitro epidermis of the efficacy of a product in protecting against acids, alkalis or solvents.
Posted in Protection and barrier effect, Protects and repairs the cutaneous barrier, Claim for medical devices

Evaluation of barrier effects on 3D reconstructed human epidermis and analysis of inflammatory cytokines

Regulatory reference: Proprietary method
Claim: Protects and repairs the cutaneous barrier
Application field: Topical products.
Description of the test: Evaluation of the protective efficacy against acids, alkalis or solvents on in vitro 3D human epidermis, paired with evaluation of the protection against pro-inflammatory substances.
Posted in Protection and barrier effect, Protects and repairs the cutaneous barrier, Claim for medical devices

Barrier effect test on 3D reconstructed skin by analysis of the transcutaneous passage of caffeine

Regulatory reference: Proprietary method
Claim: Barrier effect
Application field: Solutions or finished products.
Description of the test: Quantification by HPLC of the amount of caffeine permeating the skin barrier of in vitro 3D skin in Franz’s cells, compared to the total titer of the same substance in the applied product.
Posted in Barrier effect, Protection and barrier effect, Claim for medical devices

Barrier effect test on 3D reconstructed skin by analysis of the transcutaneous passage of testosterone

Regulatory reference: Proprietary method
Claim: Barrier effect
Application field: Solutions or finished products.
Description of the test: Quantification by HPLC of the amount of testosterone permeating the skin barrier of in vitro 3D skin in Franz’s cells, compared to the total titer of the same substance in the applied product.
Posted in Barrier effect, Protection and barrier effect, Claim for medical devices

Protection and barrier effect test on oral epithelium with analysis of IL1-Alpha expression

Regulatory reference: Proprietary method
Claim: Protects and repairs the cutaneous barrier
Application field: Topycal products.
Description of the test: Measurement of inhibitory efficacy of an active ingredient or finished product against the adhesion of Staphylococcus aureus to epithelial cells.
Posted in Protection and barrier effect, Protects and repairs the cutaneous barrier, Claim for medical devices

Barrier effect test against microbial strains

Regulatory reference: Proprietary method
Claim: Inhibition of bacterial adhesion
Application field: Raw ingredients or finished products.
Description of the test: Measurement of inhibitory efficacy of an active ingredient or finished product against the adhesion of Staphylococcus aureus to epithelial cells.
Posted in Protection and barrier effect, Inhibition of bacterial adhesion, Claim for medical devices

Percutaneous absorption test

Regulatory reference: Proprietary method
Claim: Evaluation of transcutaneous absorption
Application field: Solutions or finished products.
Description of the test: Quantification by HPLC of the amount of an active ingredient permeating the skin barrier of artificial or in vitro 3D skin in Franz’s cells, compared to the total titer of the same substance in the applied product.
Posted in Protection and barrier effect, Substance-based, Claim for medical devices, Evaluation of transcutaneous absorption

Stability test

Regulatory reference: ICH or ISO
Claim: Accelerated stability tests
Application field: Medical devices and cosmetics.
Description of the test: Accelerated stability test according to ICH guidelines and ISO regulatory requirements, for medical devices and cosmetics.
Posted in Fabrics, plastics and polymer patches, Heating and cooling products, Mucoadhesive products, Protection and barrier effect, Substance-based, Surgical devices and medications, Make up, Claim for cosmetics, Claim for medical devices, Accelerated stability tests

Biocompatibility test

Regulatory reference: ISO 10993-10
Claim: Biocompatible
Application field: Finished products, textiles, solid products by eluate.
Description of the test: Biocompatibility test: triple analysis for irritation, cytotoxicity and sensitization potential.
Posted in Condom and vaginal products, Fabrics, plastics and polymer patches, Heating and cooling products, Mucoadhesive products, Protection and barrier effect, Raw materials for medical devices, Substance-based, Surgical devices and medications, Claim for medical devices, Biocompatible

Evaluation of bacterial adhesion on mammal cells

Regulatory reference: Proprietary method
Claim: Inhibition of bacterial adhesion
Application field: Medical devices design to inhibit bacterial adhesion.
Description of the test: Evaluation of bacterial adhesion on mammal cells, performed on the CACO-2 cell line.
Posted in Protection and barrier effect, Detergents, Claim for cosmetics, Claim for medical devices, Inhibition of bacterial adhesion

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