Publications

Regulatory reference:	Proprietary method
Claim:	Tanning
Application field:	Active ingredients or finished products.
Description of the test:	Quantification of the increase of melanin synthesis in human melanoma cells treated with the sample substance or product in comparison with untreated controls. The same test can be used to quantify a reduction in melanin synthesis.

Regulatory reference:	Proprietary method
Claim:	Anti-cellulite and Sebum-regulator
Application field:	Active ingredients or finished products.
Description of the test:	Analysis of the activation of the activity of enzymatic lipase in a controlled triglyceride hydrolysis reaction.

Regulatory reference:	Proprietary method
Claim:	Anti-cellulite
Application field:	Active ingredients or finished products.
Description of the test:	Evaluation of the reduction of intracellular lipid accumulation in adipocyte cells treated with several concentrations of the tested product, in comparison to untreated adipocytes.

Regulatory reference:	Proprietary method
Claim:	Antioxidant
Application field:	Raw ingredients or finished products.
Description of the test:	Quantification of the efficacy of the sample in inhibiting cytoplasmic oxidation phenomenon and protecting the skin cell model (immortalized human keratinocytes) from damaged caused by ROS.

Regulatory reference:	Proprietary method
Claim:	Activates the synthesis of collagen, elastin, fibronectin
Application field:	Finished products and active ingredients.
Description of the test:	Quantitative analysis of the effect of the tested product in increasing the synthesis of collagen and elastin. The test is performed on several concentration and time points using real time PCR on cultured cell lines. The test can be performed on human keratinocytes or fibroblasts.

Regulatory reference:	Proprietary method
Claim:	Anti-aging and Redensifies and tones the epidermis
Application field:	Finished products and active ingredients.
Description of the test:	Quantitative evaluation of the efficacy of a product or active ingredient in increasing cell proliferation and protein synthesis. MTT test and protein quantification at different time intervals. The test can be performed on human keratinocytes or fibroblasts.

Regulatory reference:	Proprietary method
Claim:	Hydrates the skin
Application field:	Finished products.
Description of the test:	Evaluation of the moisturizing efficacy of chemical substances or mixtures.

Regulatory reference:	Proprietary method
Claim:	Inhibition of bacterial adhesion
Application field:	Medical devices design to inhibit bacterial adhesion.
Description of the test:	Evaluation of bacterial adhesion on mammal cells, performed on the CACO-2 cell line.

Regulatory reference:	ISO 11930 for cosmetics; European Pharmacopoeia for medical devices
Claim:	Efficacy of preservatives
Application field:	Cosmetics and medical devices.
Description of the test:	Challenge test for the evaluation of the efficacy of preservative systems according to ISO guidelines (for cosmetics) and European Pharmacopoeia (for medical devices).

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