In recent years, the concept of skin longevity has gained increasing attention. It’s not just a beauty trend, but it is important also in the science field because is a science-driven approach to maintaining healthy, resilient skin over time.
One of the major factors influencing how our skin ages, among others, is oxidative stress, a process deeply connected to the exposome, the totality of environmental and lifestyle factors our skin encounters every day, like pollution, mental state caused by lifestyle etc, and that can cause problems to the skin.
The exposome and oxidative stress
The exposome includes everything from UV radiation, pollution, and cigarette smoke to diet, stress, and lack of sleep. These elements generate reactive oxygen species (ROS), unstable molecules that damage lipids, proteins, and DNA within skin cells. Over time, this oxidative stress compromises the skin’s structure and function, leading to premature aging, dullness, loss of elasticity, and the appearance of wrinkles.
Antioxidants: the skin’s defense
Antioxidants are the skin’s natural defense mechanism against oxidative stress. They neutralize ROS before they can trigger damage, helping to preserve the integrity of skin cells and delay visible aging signs.
Modern cosmetic formulations enriched with antioxidant ingredients, such as vitamins C and E, polyphenols, flavonoids, and botanical extracts, are designed to protect the skin barrier and support its natural repair mechanisms. When used regularly, these products contribute to long-term skin health and longevity, beyond short-term beauty results.
From the lab to the skin: assessing antioxidant efficacy
To substantiate antioxidant claims, scientific testing is essential. At our laboratories, we conduct in vitro assays to measure antioxidant activity of cosmetic ingredients and formulations. These tests allow us to screen and quantify their ability to neutralize free radicals and chelate metals responsible for oxidative reactions.
Building on this foundation, we have also introduced a new FRAP (Ferric Reducing Antioxidant Power) assay for in vivo evaluation. This innovative method measures the antioxidant capacity directly on volunteers during clinical studies, providing a deeper understanding of how formulations act in real skin conditions.
A different approach to skin longevity
By combining advanced antioxidant testing with a scientific approach to formulation, we aim to help our partner to develop cosmetic products that not only protect against oxidative stress but actively promote skin longevity. This aligns with a modern vision of skincare: prevention, protection, and proactive care for skin that remains radiant and resilient over time.
In conclusion, promoting skin longevity goes far beyond aesthetic goals because it represents a science-based commitment to protecting and preserving the skin’s health over time. Through rigorous laboratory and clinical testing, such as in vitro and in vivo antioxidant assays, we can better understand and validate their real efficacy on the skin and contribute to enhance immediate appearance and also strengthen the skin’s resilience for the future.
